Human CD257 (BAFF, BLyS) Synthetic Peptide

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Product Description

This peptide corresponds to 16 amino acids near the carboxy terminus of human BAFF. PEP-0066 can be used as a blocking peptide with polyclonal antibody PA5-19941. BAFF is a membrane bound cytokine expressed by B cell lineage cells. The soluble form of the cytokine binds to the receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. BAFF is a potent B cell activator, and important for the proliferation and differentiation of B cells. BAFF is also expressed by T lymphocytes and has been shown to promote T cell activation and survival. Isoforms representing alternatively spliced, and glycosylated variants have been identified.