Bovine Rhodopsin (aa 338-348) Synthetic Peptide

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Product Description

PEP-174 is a 12 amino acid synthetic peptide whose sequence is derived from bovine rhodopsin protein. The sequence of this peptide is (amino to carboxy terminus): C-S (338)-K-T-E-T-S-Q-V-A-P-A (348) This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and bovine rhodopsin, catalog # PA1-729. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions. Reconstitute with 0.1 mL of distilled water. Visual pigments such as rhodopsin and porphyropsin are light-absorbing molecules that mediate vision. Rhodopsin consists of an apoprotein, opsin, covalently linked to 11-cis-retinal. This receptor is coupled to the activation of phospholipase C. Porphyropsin consists of opsin covalently linked to 11-cis 3,4-didehydroretinal.