Mouse VCP (aa 792-806) Synthetic Peptide

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Product Description

PEP-239 is a 16 amino acid synthetic peptide corresponding to amino acid residues 792-806 from mouse VCP. The sequence of this peptide is (amino to carboxy terminus): C G (792) G S V Y T E D N D D D L Y G (806). This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, catalog # MA3-004. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions. Reconstitute with 0.1 mL of distilled water. The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.