Nestin Polyclonal Antibody
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA5143578 | 100 µL | 439,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant construct, amino acids 317-630 of the human protein expressed in and purified from E. coli. |
| Host | Ck |
| Genebank | NES |
| Isotype | IgY |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Pab |
| Format | Liquid; , with 5mM sodium azide |
| Working Dilution | Immunocytochemistry (1:1,000-1:2,000), Western Blot (1:5,000), Immunohistochemistry (Paraffin) (1... |
| Conjugation | Unconjugated |
| Storage Conditions | 4° C |
| Disclaimer | Alternative CatNo: PA5-143578 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
