SARS-CoV-2 Spike Protein RBD Monoclonal Antibody (5G8)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| MA547350 | 500 µL | 1'520,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ICC, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant SARS-CoV2 S-Protein ACE2 binding domain expressed in and purified from E. coli |
| Host | Ms |
| Clone Number | [5G8] |
| Isotype | IgG1 |
| Crossreactivity | Virus |
| Clonality | Mab |
| Format | Liquid; PBS; , with 50% glycerol and 5mM sodium azide |
| Concentration | 1 mg/mL |
| Working Dilution | Immunocytochemistry (1:1,000), Immunohistochemistry (Assay-dependent), Western Blot (1:1,000-1:3,... |
| Purity | Protein A/G |
| Conjugation | Unconjugated |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Disclaimer | Alternative CatNo: MA5-47350 |
| Product Line | Coronavirus |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
