SARS-CoV-2-IN-81


Catalog Number Pack Size List Price* Quantity
HY-161261-1ST Get quote   Inquire

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Product Description

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SARS-CoV-2-IN-81 (compound 12e) is a potent AAK1 inhibitor with an IC50 value of 9.38 nM. SARS-CoV-2-IN-81 shows anti-viral property against SARS-CoV-2. SARS-CoV-2-IN-81 attenuates AAK1-induced phosphorylation of AP2M1 threonine 156 and disrupts the direct interaction between AP2M1 and ACE2, ultimately inhibiting SARS-CoV-2 infection[1].

Category Inhibitor
Supplier MedChem Express
Regulatory Status RUO
Research Field Infection, Anti-infection,Neuronal Signaling
Format Solubility: 10 mM in DMSO
Grade Clinical information: No Development Reported
Molecular Formula C25H20N4O2
Molecular Weight 408.45
Product Line Coronavirus
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room temperature
Material Safety Data Sheet Download PDF