TH6342
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-161296-1ST | Get quote | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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TH6342 is a SAMHD1 modulator that binds to pretetrameric SAMHD1 and prevents its oligomerization and allosteric activation. SAMHD1 is a dNTP triphosphohydrolase and an HIV-1 restriction factor. SAMHD1 can limit the replication of retroviruses and DNA viruses and has antiviral effects. The inhibitory mechanism of TH6342 does not occupy the SAMHD1 nucleotide-binding pocket, gently binds the target, and functions as a chemical probe[1].
Category | Biochemicals |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Infection, Anti-infection |
Format | Solubility: 10 mM in DMSO |
Grade | Clinical information: No Development Reported |
Molecular Formula | C19H16ClN5 |
Molecular Weight | 349.82 |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room temperature |
Material Safety Data Sheet | Download PDF |