TH6342


Catalog Number Pack Size List Price* Quantity
HY-161296-1ST Get quote   Inquire

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Product Description

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TH6342 is a SAMHD1 modulator that binds to pretetrameric SAMHD1 and prevents its oligomerization and allosteric activation. SAMHD1 is a dNTP triphosphohydrolase and an HIV-1 restriction factor. SAMHD1 can limit the replication of retroviruses and DNA viruses and has antiviral effects. The inhibitory mechanism of TH6342 does not occupy the SAMHD1 nucleotide-binding pocket, gently binds the target, and functions as a chemical probe[1].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Infection, Anti-infection
Format Solubility: 10 mM in DMSO
Grade Clinical information: No Development Reported
Molecular Formula C19H16ClN5
Molecular Weight 349.82
Link To Supplier http://www.medchemexpress.com
Shipping Details Room temperature
Material Safety Data Sheet Download PDF