Recombinant Human G-CSF Protein
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| BP000175-GD16-50uG | 50 ug | 315,00 | Add | |
| BP000175-GD16-300uG | 300 ug | 574,00 | Add | |
| BP000175-GD16-1MG | 1 mg | 1'349,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Human Granulocyte-Colony-Stimulating Factor (G-CSF), a 20 kDa glycoprotein containing internal disulfide bonds, induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. G-CSF functions through the Janus kinase (JAK)/signal transducer and activator of transcription (STAT), Ras/mitogen-activated protein kinase (MAPK), and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signal transduction pathway. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. Bacterial endotoxins, TNF, Interleukin-1, and GM-CSF induce the synthesis of G-CSF while prostaglandin E2 inhibits its synthesis. Interleukin-17 induces the secretion of G-CSF in epithelial, endothelial, and fibroblastic cells.
| Category | Protein |
| Supplier | Syd Labs |
| Regulatory Status | RUO |
| Host | E.coli |
| Clonality | Recombi |
| Format | In 0.2 um filtered solution of 10 mM HAc-NaAc, 150 mM NaCl, 0.004% Tween 80, 5% Mannitol, pH 4.0 |
| Purity | > 95% by SEC-HPLC and reducing SDS-PAGE |
| Storage Conditions | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt if stored at 4°C as supplied. |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.sydlabs.com |
| Shipping Details | Ice pack |
| Material Safety Data Sheet | Download PDF |
