Recombinant Dr. Nuclease

* CHF, excl. 8.1% VAT and shipping costs

Product Description

A genetically engineered endonuclease from Serratia marcescens, Syd Labs recombinant Dr. Nuclease degrades all forms of DNA and RNA while having no proteolytic activity. The endonuclease activity is effective over a wide range of conditions and the enzyme possesses an exceptionally high specific activity.Dr. Nuclease is a recombinant endonuclease produced in E. coli. Dr. Nuclease acts as an endonuclease that degrades both DNA and RNA in single-stranded, double-stranded, linear, circular, and super-coiled forms. Upon complete digestion, it digests all free nucleic acids present in solution into 5’-monophosphate-ended oligonucleotides with three to five bases.Dr. Nuclease solution is used for a variety of purposes including but not limited to: viral vaccine production; viral vector production for cell and gene therapy; prevention of cell clumping; viscosity reduction in mammalian cell extracts; viscosity reduction in E. coli cell lysates for enhanced filterability; purification of protein fragments from inclusion bodies; elimination of nucleic acids from recombinant protein; sample preparation in two-dimensional gel electrophoresis.Dr. Nuclease eliminates DNA/RNA containments in various products with ultra-speed and efficacy. Dr. Nuclease is super-effective to redu