In vivo Grade Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971), Mouse I...
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA007273.m2a-1MG | 1 mg | 256,00 | Add | |
| PA007273.m2a-5MG | 5 mg | 574,00 | Add | |
| PA007273.m2a-25MG | 25 mg | 1'349,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In vivo Grade Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971), Mouse IgG2a Kappa
The recombinant NCI m971 antibody binds to the human CD22 protein, a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice. In mice, it has been shown that CD22 blockade restores homeostatic microglial phagocytosis in aging brains.
| Category | Antibody |
| Supplier | Syd Labs |
| Application | EL, N, FA |
| Regulatory Status | RUO |
| Species Specificity | Hu |
| Host | Ms |
| Clone Number | [NCI m971] |
| Isotype | IgG2a |
| Clonality | Recombi |
| Format | 0.2 μM filtered solution of 1x PBS |
| Grade | in vivo |
| Purity | >95% by reducing SDS-PAGE |
| Conjugation | Unconjugated |
| Storage Conditions | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.sydlabs.com |
| Shipping Details | Ice pack |
| Material Safety Data Sheet | Download PDF |
