In vivo Grade Recombinant Anti-human CD16 Monoclonal Antibody (Clone: 3G8), Human IgG1 Fc Silent ...
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| PA007277.h1Fs-1MG | 1 mg | 197,00 | Add | |
| PA007277.h1Fs-5MG | 5 mg | 419,00 | Add | |
| PA007277.h1Fs-25MG | 25 mg | 987,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
In vivo Grade Recombinant Anti-human CD16 Monoclonal Antibody (Clone: 3G8), Human IgG1 Fc Silent Kappa
The recombinant 3G8 antibody binds to human and non-human primate CD16 or FcγRIII, a cluster of differentiation molecule found on the surface of natural killer cells, neutrophils, monocytes, macrophages, and certain T cells. CD16 consists of Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b). The most well-researched membrane receptor implicated in triggering lysis by NK cells, CD16 is a molecule of the immunoglobulin superfamily (IgSF) involved in antibody-dependent cellular cytotoxicity (ADCC). It can be used to isolate populations of specific immune cells through fluorescent-activated cell sorting (FACS) or magnetic-activated cell sorting, using antibodies directed towards CD16.The most popular human Fc blocking reagents include:Anti-human CD16 (clone 3G8), and CD32 (Clone IV.3): for flow cytometry, immunohistochemistry (IHC), and immunoprecipitation (IP). It is highly specific for FcγRII (CD32) and FcγRIII (CD16), and reduces background staining; it may not block all Fc receptors. Clones 10.1, and 22 or H22 are the most widely used anti-human FcγRI (CD64) clone for Fc blocking in flow cytometry and functional assays. It prevents non-specific Fc receptor b
| Category | Antibody |
| Supplier | Syd Labs |
| Application | EL, N, FA |
| Regulatory Status | RUO |
| Species Specificity | Hu |
| Host | Hu |
| Clone Number | [3G8] |
| Isotype | IgG1 |
| Clonality | Recombi |
| Format | 0.2 μM filtered solution of 1x PBS |
| Grade | in vivo |
| Purity | >95% by reducing SDS-PAGE |
| Conjugation | Unconjugated |
| Storage Conditions | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.sydlabs.com |
| Shipping Details | Ice pack |
| Material Safety Data Sheet | Download PDF |
