In vivo Grade Recombinant Anti-mouse CD11c Monoclonal Antibody, Hamster IgG2 Kappa (Clone: N418)

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Product Description

The hamster anti-mouse CD11c monoclonal antibody N418 (hamster IgG2 kappa) reacts with the mouse CD11c protein, the most widely used defining marker for dendritic cells (DCs). The CD11c protein helps cells stick together and is involved in many processes, including phagocytosis, cell migration, and the activation of T cells. CD11c helps cells stick together by binding to molecules like ICAM-1, fibrinogen, and iC3b, helps cells engulf and digest other cells, helps Langerhans cells activate T cells, regulates neutrophil maturation and function, and helps dendritic cells capture and activate other cells. In addition to dendritic cells and tissue macrophages, CD11c is expressed in different B-cell lymphomas, including chronic lymphocytic leukemia. CD11c-expressing cells are also found in the mouse nervous system.Our recombinant N418 antibodies have a part (variable regions) or complete amino acid sequences of the hamster anti-mouse CD11c monoclonal antibody (hybridoma clone name or number: N418).