Anti-Amyloid beta peptide antibody (A Beta 42) [MOAB-2]
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| STJA0040793-50uG | 50 µg | 782,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
MOAB-2 detects preparations enriched in U-, O-, F-A Beta 42, and U-A Beta 40 by dot-blot, and is thus a pan-specific A Beta antibody. However, MOAB-2 is selective for the more neurotoxic A Beta 42 compared to A Beta 40. Indeed, MOAB-2 demonstrated a titration against antigen concentration, and detects A Beta 40 at 2.5 pmol, but U-, O-and F-A Beta b42 at antigen concentrations as low as ~ 0.1 pmol (Youmans. KL et al., 2012; PMID: 22423893). MOAB-2 does not detect APP (Amyloid Precursor Protein). Human, rat, other species not yet tested. By Dot Blot, MOAB-2 detected rat A Beta 40 and human A Beta 40, albeit with less affinity than for A Beta 42 (Youmans KL et al., 2012).
| Category | Antibody |
| Supplier | St Johns Laboratory |
| Application | EL, ICC, IHC-F, IHC-P, IP, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant human amyloid beta protein 42 (A Beta 42) : DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA |
| Host | Ms |
| Clone Number | [MOAB-2] |
| Isotype | IgG2b,l |
| Crossreactivity | Hu, Rt |
| Clonality | Mab |
| Format | Lyophilized from PBS buffer, pH 7.4; contains no preservative. |
| Working Dilution | WB 1:2000-1:5000IHC 1:500-1:2000ICC 1:100-1:500IP 1:200-1:1000 |
| Purity | IgG |
| Conjugation | Unconjugated |
| Storage Conditions | Spin vial briefly before opening. Reconstitute in 50 µL sterile-filtered, ultrapure water to give a concentration of 1 mg/mL. Centrifuge to remove any insoluble material. Final ... |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.stjohnslabs.com |
| Material Safety Data Sheet | Download PDF |
